Main Functions:
• Potent antioxidant.
• Benefit in reversing neuropathic problems.
• Regenerates Vitamin E, Vitamin C, Glutathione and CoQ (Ubiquinone)
What is Alpha Lipoic Acid (ALA)?
Alpha-lipoic acid or ALA is a naturally occurring compound that's made in the body. It serves vital functions at the cellular level, such as energy production.
Main Functions:
• Helps regeneration and repair injured and damaged nerves.
• Reduces nerve pain and neuropathy symptoms caused by diabetes.
• Maintain normal neural function.
What is Vitamin B Complex?
The Vitamin B Complex in Bionerv® contains Vitamin B1, Vitamin B6 and Vitamin B12.
Vitamin B1 which is also called Thiamin, enables the body to use carbohydrates as energy. It is essential for glucose metabolism, and it plays a key role in nerve, muscle, and heart function. By taking Vitamin B1, it helps prevent complications in the nervous system, brain, muscles, heart, stomach, and intestines.
Vitamin B6, which is also called Pyridoxine, plays an important role in protein, fat and carbohydrate metabolism, and the creation of red blood cells and neurotransmitters. This Vitamin B6 cannot be produced in the body, so it can only be obtained by external factors.
The Vitamin B12, Cobalamin, is an important water-soluble vitamin involved in red blood cell production, brain health and DNA synthesis. This Vitamin B12 can come in different forms such as Cyanocobalamin and Methylcobalamin. In Bionerv®, Methlycobalamin is used.
Cyanocobalamin is a synthetic form of vitamin B12 that is not found in nature. Methylcobalamin is a naturally occurring form of vitamin B12 that can be obtained through supplements, as well as food sources.
Methylcobalamin may be retained better within the body.
Both have beneficial effects on health and can prevent B12 deficiencies.
NEUROPATHY
What is Neuropathy >
Peripheral neuropathy is a condition that arises when nerves that carry messages to and from the brain, spinal cord and the rest of the body are damaged or diseased.
IRRITABLE BOWEL SYNDROME
What is Irritable Bowel Syndrome (IBS) >
Irritable Bowel Syndrome is not a disease. It's a functional disorder, which means that the bowel simply does not work as it should.
(IBS) is a common disorder that affects the large intestine (colon).
(IBS) commonly causes cramping, abdominal pain, bloating, gas, diarrhea and constipation.
Is IBS common? >
• Prevalence 3 - 22% world-wide
• Reason for 20 - 50% of gastroenterology visits
• 26% prevalence among children with recurrent abdominal pain
• 40% onset before age 35
• 50% onset age 35 – 50
The Human Colon >
Colon is the part of the large intestine, the last portion of the human gastrointestinal tract. It provides 3 main functions::
• The organ for storing waste products by elimination of toxic waste material in the form of stool
• Reabsorbing water from wastes and maintaining water balance in the body
• Serves at the site for the growth of beneficial bacteria and other microorganisms
The contraction of the colon muscles and the movement of its contents is controlled by nerves, hormones, and impulses in the colon muscles. These contractions move the contents inside the colon toward the rectum. During this passage, water and nutrients are absorbed into the body, and what is left over is stool.
However, if the muscles of the colon do not contract in the right way, the contents inside the colon do not move correctly. Resulting in abdominal pain, cramps, constipation, a sense of incomplete stool movement, or diarrhea (IBS Symptoms)!
Causes of IBS >
• Abnormal gastrointestinal (GI) tract movements
• Dysbiosis due to antibiotic treatment
• A change in the nervous system communication between the GI and brain
• Sensory and motor disorders of the colon
• Dietary allergies or food sensitivities
• Neurotransmitter imbalance (decreased serotonin levels)
• Severe lack of fiber intake
• Stress
• Old age
• Infection
• Alcohol or smoking
Symptoms >
Pain, distension or abdominal discomfort and bloating
Abnormal bowel habits with periods of constipation
and / or diarrhea
Sensation of incomplete bowel movement
Mucus in the stool
What is Butyrate >
Butyrate is produced when the human gut microbiota, mainly butyrogenic bacteria ferments dietary non-digestible carbohydrates (fiber such as whole vegetables and fruits, beans and lentils, whole wheat, and other grains). Butyrate is one of the end products called short chain fatty acid, SCFA of this fermentation process. Where butyrate is used as a treatment for IBS.
How Sodium Butyrate Works As IBS treatment >
Provides energy for the colonocytes
• 70% of energy used by the colon is from butyrate
• Relieves constipation
Increase mucus production
• Provides good environment for good bacteria to grow
• Keeps pathogens and bad bacteria from causing damage
Anti-pathogenic and antimicrobial activities
• Prevents growth of bad bacteria and pathogens that harm the intestine
Regulation of immune processes through anti-inflammatory effects
• Decrease inflammation, less abdominal pain
Maintaining proper intestinal smooth muscle tone and sensitivity of visceral sensory receptors
• Less incidence of diarrhea occurrence
Regulation of apoptosis and cell division
• Ensures the intestine is in healthy and rejuvenated state
Increase epithelial permeability (intestinal barrier)
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